What’s more important to work on than life and death?
A free 18-hour crash course to transition your career into longevity.
Course
Why We Created This Course
Provide just enough overview
You don’t need to be a world-class biologist to make a difference. Longevity needs software engineers, data scientists, project coordinators, entrepreneurs, and more.
Spotlight high-impact interventions
Radical life extension won’t happen in the form of an anti-aging supplement. We created this course to direct attention and effort to where it matters.
We need all hands on deck
To have a chance of curing aging in our lifetime, we need to involve orders of magnitude more people and financial capital.
From zero biology to actionable paths to make significant contributions
Syllabus
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What the course cover
What it does NOT cover
Key takeaways
Central dogma
Biomolecules
Biochemistry
Metabolism
Homeostasis
Cells, tissues, organs
Immune system
What we don’t know
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Why we age
What is aging
Information theory
Damage accumulation theory
Intra- and Inter-species variability
Immuneaging
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Failed aging theories
Reproducibility crisis
Artisanal science
Bad incentives
Low vs. high impact
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Academia
NGOs
Government
Pharma
Startups
Funding
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Animal models
Organoid / ex-vivo models
Biomarkers
Clocks
Omics / network
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Hypothesis vs. empirical
Assays
Protocols
Automation
Repeatability
Iteration time
Drug development process
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Interventions overview
Metabolic
Pharmalogical
Reprogramming
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Damage repair
Cell / Exosome theory
Senesence
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Bioengineering overview
Gene editing
Gene delivery
Computational modeling
Machine learning
Full models
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Computational Chemistry
Kinetic models
Minimal cell project
DNA compilers
synbio CAD tools
Hibernation
Cryonics
Uploading
Prosthetics
Synthetic organs
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Lack of models / biomarkers
Lack of funding
Piecemeal science
Hype / herd mentality
Primitive tools
Personnel
Cultural aversion
Institutional misalignment
Lack of career / education paths
Lack of public databases / siloing
Lack of data protocol standards
Lack of regulatory path
Longevity Zero to One in Zuzalu
May 6-9, 2023
Zuzalu, Montenegro
This course was recorded as an in-person version of Longevity Zero to One taught by top longevity experts. It took place at Zuzalu - the pop-up city and longevity network state experiment.